Description
Human SNAPIN Recombinant Protein (N-His)
Human SNAPIN Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly21-Lys136, with an N-terminal His tag. Predicted molecular weight: 15.56 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. SNARE-associated protein Snapin (SNAPAP) is a ~14 kDa protein. Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. For research use only.
In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling. May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release through its ability to potentiate the interaction of synaptotagmin with the SNAREs and the plasma-membrane-associated protein SNAP25.
| Product Name: | Human SNAPIN Recombinant Protein (N-His) |
| SKU: | GXRP04346 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Synaptosomal-associated protein 25-binding protein, SNAPIN, Biogenesis of lysosome-related organelles complex 1 subunit 7, SNARE-associated protein Snapin, BLOC-1 subunit 7, BLOC1S7, SNAPAP, SNAP25BP, SNAP-associated protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly21-Lys136 |
| Calculated MW: | 15.56 kDa |
| UniProt: | O95295 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
