Description
Human SNRPC Recombinant Protein (N-His)
Human SNRPC Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Arg159, with an N-terminal His tag. Predicted molecular weight: 18.35 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. U1 small nuclear ribonucleoprotein C (SNRPC) is a ~17 kDa protein. Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. For research use only.
SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
| Product Name: | Human SNRPC Recombinant Protein (N-His) |
| SKU: | GXRP00765 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | U1-C, U1 snRNP C, SNRPC, U1C, U1 small nuclear ribonucleoprotein C |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Arg159 |
| Calculated MW: | 18.35 kDa |
| UniProt: | P09234 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
