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Human SNX5 Recombinant Protein (N-His)
Key Features

Human SNX5 Recombinant Protein (N-His) (GXRP04882)

SKU GXRP04882
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human SNX5 Recombinant Protein (N-His)

Human SNX5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Asp171, with an N-terminal His tag. Predicted molecular weight: 21.80 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Sorting nexin-5 (SNX5) is a ~46 kDa protein. Involved in several stages of intracellular trafficking. For research use only.

Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable).

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