Description
Human SP1 Recombinant Protein (N-His)
Human SP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu260-Ala591, with an N-terminal His tag. Predicted molecular weight: 35.77 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Transcription factor Sp1 is a ~80 kDa protein. Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. For research use only.
Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Also binds the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage.
| Product Name: | Human SP1 Recombinant Protein (N-His) |
| SKU: | GXRP00694 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | SP1, TSFP1, Transcription factor Sp1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu260-Ala591 |
| Calculated MW: | 35.77 kDa |
| UniProt: | P08047 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
