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Human SRP68 Recombinant Protein (N-His)
Key Features

Human SRP68 Recombinant Protein (N-His) (GXRP04840)

SKU GXRP04840
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human SRP68 Recombinant Protein (N-His)

Human SRP68 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met293-Gln540, with an N-terminal His tag. Predicted molecular weight: 30.65 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Signal recognition particle subunit SRP68 is a ~70 kDa protein. Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). For research use only.

The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER. The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER. Binds the signal recognition particle RNA (7SL RNA), SRP72 binds to this complex subsequently. The SRP complex possibly participates in the elongation arrest function.

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