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Human STAC3 Recombinant Protein (N-His)
Key Features

Human STAC3 Recombinant Protein (N-His) (GXRP05072)

SKU GXRP05072
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human STAC3 Recombinant Protein (N-His)

Human STAC3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser249-Ile364, with an N-terminal His tag. Predicted molecular weight: 15.67 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. SH3 and cysteine-rich domain-containing protein 3 (STAC3) is a ~41 kDa protein. Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. For research use only.

Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels. Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane.

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