Description
Human STAM2 Recombinant Protein (N-His)
Human STAM2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Leu377, with an N-terminal His tag. Predicted molecular weight: 44.53 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Signal transducing adapter molecule 2 (STAM2) is a ~58 kDa protein. Involved in intracellular signal transduction mediated by cytokines and growth factors. For research use only.
Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as a sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.
| Product Name: | Human STAM2 Recombinant Protein (N-His) |
| SKU: | GXRP00270 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | STAM2, Signal transducing adapter molecule 2, Hrs-binding protein, STAM-2, HBP |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Leu377 |
| Calculated MW: | 44.53 kDa |
| UniProt: | O75886 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
