Description
Human STARD3 Recombinant Protein (N-His)
Human STARD3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser232-Ala445, with an N-terminal His tag. Predicted molecular weight: 26.64 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. StAR-related lipid transfer protein 3 is a ~50 kDa protein. Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes. For research use only.
The sterol transport mechanism is triggered by phosphorylation of FFAT motif that leads to membrane tethering between the endoplasmic reticulum and late endosomes via interaction with VAPA and VAPB. Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes. May also mediate cholesterol transport between other membranes, such as mitochondria membrane or cell membrane. However, such results need additional experimental evidences; probably mainly mediates cholesterol transport from the endoplasmic reticulum to endosomes.
| Product Name: | Human STARD3 Recombinant Protein (N-His) |
| SKU: | GXRP09571 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | StAR-related lipid transfer protein 3; Metastatic lymph node gene 64 protein; MLN 64; Protein CAB1; START domain-containing protein 3; StARD3; STARD3; CAB1; MLN64 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser232-Ala445 |
| Calculated MW: | 26.64 kDa |
| UniProt: | Q14849 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
