Description
Human SUMO2 Recombinant Protein (N-His)
Human SUMO2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Tyr95, with an N-terminal His tag. Predicted molecular weight: 13.03 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Small ubiquitin-related modifier 2 (SUMO2) is a ~10 kDa protein. Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. For research use only.
Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2, CBX4 or ZNF451. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. Plays a role in the regulation of sumoylation status of SETX.
| Product Name: | Human SUMO2 Recombinant Protein (N-His) |
| SKU: | GXRP01897 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Ubiquitin-like protein SMT3B, SMT3B, SUMO-3, Smt3B, Sentrin-2, SMT3 homolog 2, SMT3H2, SUMO2, HSMT3, Small ubiquitin-related modifier 2, SUMO-2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Tyr95 |
| Calculated MW: | 13.03 kDa |
| UniProt: | P61956 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
