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Human TAF5L Recombinant Protein (N-His)
Key Features

Human TAF5L Recombinant Protein (N-His) (GXRP07421)

SKU GXRP07421
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human TAF5L Recombinant Protein (N-His)

Human TAF5L Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr257-His589, with an N-terminal His tag. Predicted molecular weight: 39.30 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (TAF5L) is a ~66 kDa protein. Functions as a component of the PCAF complex. For research use only.

The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex (Probable). With TAF6L, acts as an epigenetic regulator essential for somatic reprogramming. Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state.

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