Description
Human TAOK1 Recombinant Protein (N-His)
Human TAOK1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Arg283, with an N-terminal His tag. Predicted molecular weight: 34.20 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Serine/threonine-protein kinase TAO1 (TAOK1) is a ~116 kDa protein. Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. For research use only.
Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. 1. van Woerden, GM. et al. (2021) Human mutation 42, 445-459. PMID: 33565190
| Product Name: | Human TAOK1 Recombinant Protein (N-His) |
| SKU: | GXRP04608 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | MARK Kinase, Thousand and one amino acid protein kinase 1, TAOK1, KIAA1361, Prostate-derived sterile 20-like kinase 2, hKFC-B, Prostate-derived STE20-like kinase 2, PSK-2, MARKK, Kinase from chicken homolog B, Serine/threonine-protein kinase TAO1, hTAOK1, PSK2, MAP3K16 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Arg283 |
| Calculated MW: | 34.20 kDa |
| UniProt: | Q7L7X3 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
