Description
Human TCF7 Recombinant Protein (N-His-SUMO)
Human TCF7 Recombinant Protein (N-His-SUMO) is a recombinant protein expressed in E. coli, spanning Lys270-Gln354, with an N-terminal His-SUMO tag. Predicted molecular weight: 22.64 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Transcription factor 7 (TCF7) is a ~41 kDa protein. Transcriptional activator involved in T-cell lymphocyte differentiation. For research use only.
Necessary for the survival of CD4(+) CD8(+) immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. Represses expression of the T-cell receptor gamma gene in alpha-beta T-cell lineages.
| Product Name: | Human TCF7 Recombinant Protein (N-His-SUMO) |
| SKU: | GXRP04694 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | TCF-1, TCF-7, TCF7, TCF1, T-cell factor 1, T-cell-specific transcription factor 1, Transcription factor 7 |
| Tag: | N-His-SUMO |
| Expression Host: | E. coli |
| Protein Length: | Lys270-Gln354 |
| Calculated MW: | 22.64 kDa |
| UniProt: | P36402 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
