Description
Human TELO2 Recombinant Protein (N-His)
Human TELO2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Arg416, with an N-terminal His tag. Predicted molecular weight: 48.43 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Telomere length regulation protein TEL2 homolog is a ~91 kDa protein. Regulator of the DNA damage response (DDR). For research use only.
Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
| Product Name: | Human TELO2 Recombinant Protein (N-His) |
| SKU: | GXRP10790 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | KIAA0683, Protein clk-2 homolog, TELO2, Telomere length regulation protein TEL2 homolog, hCLK2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Arg416 |
| Calculated MW: | 48.43 kDa |
| UniProt: | Q9Y4R8 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
