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Human TESC Recombinant Protein (N-His)
Key Features

Human TESC Recombinant Protein (N-His) (GXRP05023)

SKU GXRP05023
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human TESC Recombinant Protein (N-His)

Human TESC Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-His214, with an N-terminal His tag. Predicted molecular weight: 26.91 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Calcineurin B homologous protein 3 (TESC) is a ~24 kDa protein. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. For research use only.

Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner.

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