Description
Human THAP1 Recombinant Protein (N-GST & C-His)
Human THAP1 Recombinant Protein (N-GST & C-His) is a recombinant protein expressed in E. coli, spanning Ser21-Glu66, with an N-terminal GST tag and a C-terminal His tag. Predicted molecular weight: 33.59 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. THAP domain-containing protein 1 (THAP1) is a ~24 kDa protein. DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. For research use only.
Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptotic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.
| Product Name: | Human THAP1 Recombinant Protein (N-GST & C-His) |
| SKU: | GXRP07647 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | THAP domain-containing protein 1, THAP1 |
| Tag: | N-GST & C-His |
| Expression Host: | E. coli |
| Protein Length: | Ser21-Glu66 |
| Calculated MW: | 33.59 kDa |
| UniProt: | Q9NVV9 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
