Description
Human THBS1 Recombinant Protein (N-His)
Human THBS1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser24-Thr221, with an N-terminal His tag. Predicted molecular weight: 23.91 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Thrombospondin-1 (THBS1) is a ~129 kDa protein. Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. For research use only.
Multifunctional, involved in inflammation, angiogenesis, wound healing, reactive oxygen species (ROS) signaling, nitrous oxide (NO) signaling, apoptosis, senescence, aging, cellular self-renewal, stemness, and cardiovascular and metabolic homeostasis. Negatively modulates dendritic cell activation and cytokine release, as part of an autocrine feedback loop, contributing to the resolution of inflammation and immune homeostasis. Ligand for receptor CD47. Modulates nitrous oxide (NO) signaling via CD47, hence playing a role as a pressor agent, supporting blood pressure.
| Product Name: | Human THBS1 Recombinant Protein (N-His) |
| SKU: | GXRP00692 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | TSP, THBS1, TSP1, Thrombospondin-1, Glycoprotein G |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser24-Thr221 |
| Calculated MW: | 23.91 kDa |
| UniProt: | P07996 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
