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Human THOP1 Recombinant Protein (N-His)
Key Features

Human THOP1 Recombinant Protein (N-His) (GXRP01780)

SKU GXRP01780
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
Purity >90% as determined by SDS-PAGE.
$458 - $2,412

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Description

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Human THOP1 Recombinant Protein (N-His)

Human THOP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn451-Thr597, with an N-terminal His tag. Predicted molecular weight: 19 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Thimet oligopeptidase (THOP1) is a ~78 kDa protein. Involved in the metabolism of neuropeptides under 20 amino acid residues long. For research use only.

Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments. Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1.

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