Description
Human TLE3 Recombinant Protein (N-His)
Human TLE3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser449-Tyr772, with an N-terminal His tag. Predicted molecular weight: 37.73 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Transducin-like enhancer protein 3 (TLE3) is a ~83 kDa protein. Transcriptional coregulator that binds to a number of transcription factors. For research use only.
Acts as a regulator of adipogenesis both by acting as a corepressor of Wnt signaling and coactivator for PPARG. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. Promotes diffentiation of white adipocytes by acting as a coactivator for PPARG and preventing the association between PRDM16 and PPARG, thereby preventing browning of white adipocytes.
| Product Name: | Human TLE3 Recombinant Protein (N-His) |
| SKU: | GXRP04205 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Transducin-like enhancer protein 3, KIAA1547, TLE3, Enhancer of split groucho-like protein 3, ESG3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser449-Tyr772 |
| Calculated MW: | 37.73 kDa |
| UniProt: | Q04726 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
