Description
Human TMEM59 Recombinant Protein (N-His)
Human TMEM59 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu36-Ser238, with an N-terminal His tag. Predicted molecular weight: 25.65 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Transmembrane protein 59 is a ~36 kDa protein. Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). For research use only.
Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding.
| Product Name: | Human TMEM59 Recombinant Protein (N-His) |
| SKU: | GXRP11682 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | C1orf8, Liver membrane-bound protein, TMEM59, Transmembrane protein 59 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu36-Ser238 |
| Calculated MW: | 25.65 kDa |
| UniProt: | Q9BXS4 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
