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Human TNS3 Recombinant Protein (N-His)
Key Features

Human TNS3 Recombinant Protein (N-His) (GXRP03249)

SKU GXRP03249
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human TNS3 Recombinant Protein (N-His)

Human TNS3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Val242, with an N-terminal His tag. Predicted molecular weight: 29.27 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Tensin-3 (TNS3) is a ~155 kDa protein. May act as a protein phosphatase and/or a lipid phosphatase (Probable). For research use only.

Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Increases DOCK5 guanine nucleotide exchange activity towards Rac and plays a role in osteoclast podosome organization. Enhances RHOA activation in the presence of DLC1.

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