Description
Human TP53INP1 Recombinant Protein (N-His-SUMO)
Human TP53INP1 Recombinant Protein (N-His-SUMO) is a recombinant protein expressed in E. coli, spanning Gln86-Ser130, with an N-terminal His-SUMO tag. Predicted molecular weight: 17.36 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Tumor protein p53-inducible nuclear protein 1 (TP53INP1) is a ~27 kDa protein. Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. For research use only.
Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function.
| Product Name: | Human TP53INP1 Recombinant Protein (N-His-SUMO) |
| SKU: | GXRP05713 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Stress-induced protein, P53DINP1, TP53INP1, Tumor protein p53-inducible nuclear protein 1, p53DINP1, SIP, p53-dependent damage-inducible nuclear protein 1 |
| Tag: | N-His-SUMO |
| Expression Host: | E. coli |
| Protein Length: | Gln86-Ser130 |
| Calculated MW: | 17.36 kDa |
| UniProt: | Q96A56 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
