Description
Human TPK1 Recombinant Protein (N-His)
Human TPK1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ser243, with an N-terminal His tag. Predicted molecular weight: 29.43 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Thiamine pyrophosphokinase 1 (TPK1) is a ~27 kDa protein. Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate (TPP) utilizing UTP and therefore links the biosynthesis of TPP to pyrimidines metabolism. For research use only.
By producing thiamine pyrophosphate, a cofactor of the mitochondrial pyruvate dehydrogenase indirectly regulates pyruvate oxidation and lipogenesis. Although it can also catalyze thiamine phosphorylation using ATP and CTP in vitro, it does so with significantly lower efficiency and without physiological relevance evidence.
| Product Name: | Human TPK1 Recombinant Protein (N-His) |
| SKU: | GXRP04418 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | hTPK1, Thiamine pyrophosphokinase 1, Thiamin pyrophosphokinase 1, TPK1, PP20, Placental protein 20 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Ser243 |
| Calculated MW: | 29.43 kDa |
| UniProt: | Q9H3S4 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
