Description
Human TRAF6 Recombinant Protein (N-His)
Human TRAF6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln348-Asp504, with an N-terminal His tag. Predicted molecular weight: 20.57 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. TNF receptor-associated factor 6 (TRAF6) is a ~59 kDa protein. E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as ECSIT, IKBKG, IRAK1, AKT1 and AKT2. For research use only.
Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF-kappa-B and JUN. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes.
| Product Name: | Human TRAF6 Recombinant Protein (N-His) |
| SKU: | GXRP03135 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | RING finger protein 85, RING-type E3 ubiquitin transferase TRAF6, Interleukin-1 signal transducer, TRAF6, TNF receptor-associated factor 6, E3 ubiquitin-protein ligase TRAF6, RNF85 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gln348-Asp504 |
| Calculated MW: | 20.57 kDa |
| UniProt: | Q9Y4K3 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
