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Human TRAIL / TNFSF10 ELISA Kit

SKU:
HUFI00376
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P50591
Sensitivity:
9.375pg/ml
Range:
15.625-1000pg/ml
ELISA Type:
Sandwich
Synonyms:
TRAIL, TNFSF10, CD253, Apo-2 ligand, APO2L, Apo-2Ltumor necrosis factor, ligand family, member 10
Reactivity:
Human
Research Area:
Cell Death
€499
Frequently bought together:

Description

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Human TRAIL / TNFSF10 ELISA Kit

TRAIL / TNFSF10 is a cytokine that binds to several members of TNF receptor superfamily. TRAIL / TNFSF10 preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. The binding of TRAIL / TNFSF10 to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Diseases associated with TRAIL / TNFSF10 include Thoracic Cancer and Pancreatic Cancer.