Description
Human TRIM15 Recombinant Protein (N-His)
Human TRIM15 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu80-Pro275, with an N-terminal His tag. Predicted molecular weight: 25.55 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. E3 ubiquitin-protein ligase TRIM15 is a ~52 kDa protein. E3 ubiquitin ligase that plays a role in several processes including innate antiviral immnity, cell migration and chemotaxis. For research use only.
Acts as a 'Lys-63'-specific ubiquitin ligase for MAPK1/ERK2 and MAPK3/ERK1, promoting their activation by facilitating their interaction with MAP2K1 and MAP2K2. Also plays a role in cell migration and chemotaxis by acting as a stable focal adhesion component upon recruitment by multi-adapter protein paxillin/PXN. Functions in the RIGI-mediated interferon induction pathway upstream or at the level of MAVS. Inhibits NF-kappa-B activation by turnover of 'Lys-63'-linked ubiquitination of MAP3K7/TAK1.
| Product Name: | Human TRIM15 Recombinant Protein (N-His) |
| SKU: | GXRP04600 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ZNF178, Tripartite motif-containing protein 15, TRIM15, ZNFB7, Zinc finger protein 178, RNF93, RING finger protein 93, Zinc finger protein B7 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu80-Pro275 |
| Calculated MW: | 25.55 kDa |
| UniProt: | Q9C019 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
