Description
Human TRIM63 Recombinant Protein (N-His-SUMO & C-Strep)
Human TRIM63 Recombinant Protein (N-His-SUMO & C-Strep) is a recombinant protein expressed in E. coli, spanning Gly11-Arg112, with an N-terminal His-SUMO tag and a C-terminal Strep tag. Predicted molecular weight: 25.30 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. E3 ubiquitin-protein ligase TRIM63 is a ~40 kDa protein. E3 ubiquitin ligase. For research use only.
Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins.
| Product Name: | Human TRIM63 Recombinant Protein (N-His-SUMO & C-Strep) |
| SKU: | GXRP04125 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | IRF, RNF28, Iris RING finger protein, SMRZ, MURF1, MuRF-1, MuRF1, Striated muscle RING zinc finger protein, Tripartite motif-containing protein 63, TRIM63, E3 ubiquitin-protein ligase TRIM63, Muscle-specific RING finger protein 1, RING finger protein 28, RING-type E3 ubiquitin transferase TRIM63 |
| Tag: | N-His-SUMO & C-Strep |
| Expression Host: | E. coli |
| Protein Length: | Gly11-Arg112 |
| Calculated MW: | 25.30 kDa |
| UniProt: | Q969Q1 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
