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Human TTF1 Recombinant Protein (N-His)
Key Features

Human TTF1 Recombinant Protein (N-His) (GXRP11514)

SKU GXRP11514
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human TTF1 Recombinant Protein (N-His)

Human TTF1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala489-Tyr868, with an N-terminal His tag. Predicted molecular weight: 46.97 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Transcription termination factor 1 is a ~103 kDa protein. Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. For research use only.

Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.

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