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Human TUFM Recombinant Protein (N-His)
Key Features

Human TUFM Recombinant Protein (N-His) (GXRP04729)

SKU GXRP04729
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human TUFM Recombinant Protein (N-His)

Human TUFM Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp67-Gly452, with an N-terminal His tag. Predicted molecular weight: 44.84 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Elongation factor Tu, mitochondrial (TUFM) is a ~49 kDa protein. GTP hydrolase that promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. For research use only.

Participates in mitochondrial translation. Also plays a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIGI-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy.

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