Description
Human TYROBP Recombinant Protein (N-His)
Human TYROBP Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu22-Lys113, with an N-terminal His tag. Predicted molecular weight: 12.34 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. TYRO protein tyrosine kinase-binding protein is a ~12 kDa protein. Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors. For research use only.
TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation. Also has an inhibitory role in some cells. Non-covalently associates with activating receptors of the CD300 family to mediate cell activation. Also mediates cell activation through association with activating receptors of the CD200R family.
| Product Name: | Human TYROBP Recombinant Protein (N-His) |
| SKU: | GXRP10747 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | DAP12, DNAX-activation protein 12, KAR-associated protein, KARAP, Killer-activating receptor-associated protein, TYRO protein tyrosine kinase-binding protein, TYROBP |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu22-Lys113 |
| Calculated MW: | 12.34 kDa |
| UniProt: | O43914 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
