Description
Human UBE2C Recombinant Protein (N-His)
Human UBE2C Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala2-Pro179, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ubiquitin-conjugating enzyme E2 C (UBE2C) is a ~19 kDa protein. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. For research use only.
In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
| Product Name: | Human UBE2C Recombinant Protein (N-His) |
| SKU: | GXRP00062 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | E2 ubiquitin-conjugating enzyme C, UBE2C, Ubiquitin carrier protein C, UbcH10, (E3-independent) E2 ubiquitin-conjugating enzyme C, Ubiquitin-conjugating enzyme E2 C, Ubiquitin-protein ligase C, UBCH10 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ala2-Pro179 |
| UniProt: | O00762 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |