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Human UBE2C Recombinant Protein (N-His)
Key Features

Human UBE2C Recombinant Protein (N-His) (GXRP00062)

SKU GXRP00062
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human UBE2C Recombinant Protein (N-His)

Human UBE2C Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala2-Pro179, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ubiquitin-conjugating enzyme E2 C (UBE2C) is a ~19 kDa protein. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. For research use only.

In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

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