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Human UCP3 Recombinant Protein (N-His)
Key Features

Human UCP3 Recombinant Protein (N-His) (GXRP01847)

SKU GXRP01847
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human UCP3 Recombinant Protein (N-His)

Human UCP3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Phe312, with an N-terminal His tag. Predicted molecular weight: 36.38 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Putative mitochondrial transporter UCP3 is a ~34 kDa protein. Putative transmembrane transporter that plays a role in mitochondrial metabolism via an as yet unclear mechanism. For research use only.

Originally, this mitochondrial protein was thought to act as a proton transmembrane transporter from the mitochondrial intermembrane space into the matrix, causing proton leaks through the inner mitochondrial membrane, thereby uncoupling mitochondrial membrane potential generation from ATP synthesis. However, this function is controversial and uncoupling may not be the function, or at least not the main function, but rather a consequence of more conventional metabolite transporter activity.

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