Description
Human UGT1A3 Recombinant Protein (N-His)
Human UGT1A3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly29-Asp491, with an N-terminal His tag. Predicted molecular weight: 54.88 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. UDP-glucuronosyltransferase 1A3 is a ~60 kDa protein. UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. For research use only.
Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds. Catalyzes the glucuronidation of endogenous estrogen hormones such as estradiol and estrone. Contributes to bile acid (BA) detoxification by catalyzing the glucuronidation of BA substrates, which are natural detergents for dietary lipids absorption. Involved in the glucuronidation of calcidiol, which is the major circulating form of vitamin D3, essential for the regulation of calcium and phosphate homeostasis.
| Product Name: | Human UGT1A3 Recombinant Protein (N-His) |
| SKU: | GXRP11291 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | EC:2.4.1.17, GNT1, UDP-glucuronosyltransferase 1-3, UDP-glucuronosyltransferase 1-C, UDP-glucuronosyltransferase 1A isoform 3, UDP-glucuronosyltransferase 1A3, UDPGT 1-3, UGT-1C, UGT1, UGT1*3, UGT1-03, UGT1.3, UGT1A3, UGT1C |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly29-Asp491 |
| Calculated MW: | 54.88 kDa |
| UniProt: | P35503 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
