Description
Human VIL1 Recombinant Protein (N-His)
Human VIL1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Lys320, with an N-terminal His tag. Predicted molecular weight: 37.93 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Villin-1 (VIL1) is a ~92 kDa protein. Epithelial cell-specific Ca(2+)-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments. For research use only.
Plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Binds phosphatidylinositol 4,5-bisphosphate (PIP2) and lysophosphatidic acid (LPA); binds LPA with higher affinity than PIP2. Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities. Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity.
| Product Name: | Human VIL1 Recombinant Protein (N-His) |
| SKU: | GXRP00770 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | VIL1, Villin-1, VIL |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Lys320 |
| Calculated MW: | 37.93 kDa |
| UniProt: | P09327 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
