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Human VIM/Vimentin Recombinant Protein (N-His)
Key Features

Human VIM/Vimentin Recombinant Protein (N-His) (GXRP00737)

SKU GXRP00737
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
Purity >90% as determined by SDS-PAGE.
$458 - $2,412

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Description

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Human VIM/Vimentin Recombinant Protein (N-His)

Human VIM/Vimentin Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Glu466, with an N-terminal His tag. Predicted molecular weight: 55.81 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Vimentin is a ~53 kDa protein. Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. For research use only.

Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. Plays a role in cell directional movement, orientation, cell sheet organization and Golgi complex polarization at the cell migration front. Protects SCRIB from proteasomal degradation and facilitates its localization to intermediate filaments in a cell contact-mediated manner. May promote axon outgrowth and motor fiber repair via DSP-mediated recruitment to outgrowth tips.

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