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Human WDFY4 Recombinant Protein (N-His)
Key Features

Human WDFY4 Recombinant Protein (N-His) (GXRP11435)

SKU GXRP11435
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human WDFY4 Recombinant Protein (N-His)

Human WDFY4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met2863-Gly3184, with an N-terminal His tag. Predicted molecular weight: 36.76 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. WD repeat- and FYVE domain-containing protein 4 is a ~353 kDa protein. Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. For research use only.

Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Also plays a role in B-cell survival through regulation of autophagy.

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