Description
Human WDR5 Recombinant Protein (N-His)
Human WDR5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Lys120, with an N-terminal His tag. Predicted molecular weight: 14.99 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. WD repeat-containing protein 5 (WDR5) is a ~36 kDa protein. Contributes to histone modification. For research use only.
May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues.
| Product Name: | Human WDR5 Recombinant Protein (N-His) |
| SKU: | GXRP01898 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | WDR5, BMP2-induced 3-kb gene protein, WD repeat-containing protein 5, BIG3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Lys120 |
| Calculated MW: | 14.99 kDa |
| UniProt: | P61964 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
