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Human WNT7A Recombinant Protein (N-His)
Key Features

Human WNT7A Recombinant Protein (N-His) (GXRP04612)

SKU GXRP04612
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human WNT7A Recombinant Protein (N-His)

Human WNT7A Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp57-Lys349, with an N-terminal His tag. Predicted molecular weight: 35.22 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Protein Wnt-7a (WNT7A) is a ~39 kDa protein. Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. For research use only.

Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation. Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal neural stem cell proliferation in the hippocampus dentate gyrus.

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