Description
Human XAF1 Recombinant Protein (N-His)
Human XAF1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Asp175, with an N-terminal His tag. Predicted molecular weight: 22.61 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. XIAP-associated factor 1 is a ~34 kDa protein. Seems to function as a negative regulator of members of the IAP (inhibitor of apoptosis protein) family. For research use only.
Inhibits anti-caspase activity of BIRC4. Induces cleavage and inactivation of BIRC4 independent of caspase activation. Mediates TNF-induced apoptosis and is involved in apoptosis in trophoblast cells. May inhibit BIRC4 indirectly by activating the mitochondrial apoptosis pathway.
| Product Name: | Human XAF1 Recombinant Protein (N-His) |
| SKU: | GXRP09691 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | XIAP-associated factor 1; BIRC4-binding protein; XAF1; BIRC4BP; XIAPAF1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Asp175 |
| Calculated MW: | 22.61 kDa |
| UniProt: | Q6GPH4 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
