Description
Human XRN2 Recombinant Protein (N-His)
Human XRN2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu513-Ser737, with an N-terminal His tag. Predicted molecular weight: 28.23 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. 5'-3' exoribonuclease 2 (XRN2) is a ~108 kDa protein. Possesses 5'->3' exoribonuclease activity. For research use only.
May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites.
| Product Name: | Human XRN2 Recombinant Protein (N-His) |
| SKU: | GXRP05040 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | XRN2, DHP protein, 5'-3' exoribonuclease 2, DHM1-like protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu513-Ser737 |
| Calculated MW: | 28.23 kDa |
| UniProt: | Q9H0D6 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
