Description
Human ZNF93 Recombinant Protein (N-His)
Human ZNF93 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Phe145-Pro620, with an N-terminal His tag. Predicted molecular weight: 56.68 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Zinc finger protein 93 is a ~70 kDa protein. Transcription factor specifically required to repress long interspersed nuclear element 1 (L1) retrotransposons: recognizes and binds L1 sequences and repress their expression by recruiting a repressive complex containing TRIM28/KAP1. For research use only.
Not able to repress expression of all subtypes of L1 elements. Binds to the 5' end of L1PA4, L1PA5 and L1PA6 subtypes, and some L1PA3 subtypes. Does not bind to L1PA7 or older subtypes nor at the most recently evolved L1PA2 and L1Hs. 50% of L1PA3 elements have lost the ZNF93-binding site, explaining why ZNF93 is not able to repress their expression.
| Product Name: | Human ZNF93 Recombinant Protein (N-His) |
| SKU: | GXRP11292 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ZNF505, ZNF93, Zinc finger protein 505, Zinc finger protein 93, Zinc finger protein HTF34 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Phe145-Pro620 |
| Calculated MW: | 56.68 kDa |
| UniProt: | P35789 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
