The IFN-beta Monoclonal Antibody (CAB22740) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in mice, is highly specific to human IFN-Beta and is validated for use in various applications such as ELISA, Western blot, and immunohistochemistry.Interferon-beta is a type I interferon that helps to regulate the immune response by promoting anti-viral activities and modulating inflammation. Research on IFN-Beta is essential for understanding its role in autoimmune diseases like multiple sclerosis and systemic lupus erythematosus, as well as its potential as a therapeutic target for these conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
IFN-beta Monoclonal Antibody
SKU:
CAB22740
Size:
20μL, 100μL
Reactivity:
Mouse
Clone Number:
ARC58590
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Enables cytokine activity and type I interferon receptor binding activity. Involved in B cell proliferation; cellular response to virus; and type I interferon signaling pathway. Acts upstream of or within several processes, including cellular response to organic cyclic compound; defense response to other organism; and negative regulation of osteoclast differentiation. Located in extracellular space. Is expressed in embryo and liver. Human ortholog(s) of this gene implicated in COVID-19. Orthologous to human IFNB1 (interferon beta 1).
Purification Method
Affinity purification
Gene ID
15977
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of Recombinant Mouse IFN-beta Protein (RP01076) using IFN-beta Rabbit mAb (CAB22740) at 1:6000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 10ng/5ng/1ng per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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