Imeroprubart Antibody is a research-grade biosimilar monoclonal antibody targeting FCGRT/FCRN. It is a human IgG1, lambda2 antibody. Reactivity: Human. Supplied as a liquid. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% as determined by SDS-PAGE. For research use only.
IgG receptor FcRn large subunit p51 (FCGRT) is a ~39 kDa protein. Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation.
Product Name:
Imeroprubart Antibody
SKU:
GXBS02575
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Target:
FCGRT/FCRN
Isotype:
IgG1, lambda2
Host Species:
Human
Reactivity:
Human
Applications:
ELISA, FACS, Functional assay, Research in vivo
Synonyms:
2894136-80-0
Purity:
>95% as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
