The Integrin alpha 6 (ITGA6/CD49f) Antibody (CAB3236) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.Integrin alpha 6 is a key player in various physiological and pathological processes, such as embryonic development, tissue regeneration, and cancer metastasis. By targeting this protein with the Integrin Alpha 6 Polyclonal Antibody, researchers can detect and analyze its expression and localization in different cell types, providing insights into its functional role in cell behavior.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Integrin alpha 6 (ITGA6/CD49f) Antibody
SKU:
CAB3236
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Cell Membrane, Lipid-Anchor, Single-Pass Type I Membrane Protein.
Calculated MW:
127kDa
Observed MW:
125kDa
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
3655
RRID
AB_2765002
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Integrin alpha 6 (ITGA6/CD49f) Rabbit pAb (CAB3236) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
