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Integrin alpha V (ITGAV/CD51) Rabbit Monoclonal Antibody (CAB19071)

SKU:
CAB19071
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
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Description

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Product Name:Integrin alpha V (ITGAV/CD51) Rabbit Monoclonal Antibody
SKU:CAB19071
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 949-1048 of human Integrin alpha V (ITGAV/CD51) (NP_002201.2).
Sequence:SLKS SASF NVIE FPYK NLPI EDIT NSTL VTTN VTWG IQPA PMPV PVWV IILA VLAG LLLL AVLV FVMY RMGF FKRV RPPQ EEQE REQL QPHE NGEG NSET
Tested Applications:WB IHC-P ELISA FC (intra)
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 FC (intra),1:50 - 1:200
Synonyms:CD51; MSK8; VNRA; VTNR; Integrin alpha V (ITGAV/CD51)
Positive Sample:A549,MCF7,NIH/3T3,C6,Mouse brain,Mouse kidney,Rat kidney,Rat lung
Conjugate:Unconjugated
Cellular Localization:Membrane, Single-pass type I membrane protein.
Calculated MW:116kDa
Observed MW:140kDa

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Purification Method:Affinity purification
Gene ID:3685
Clone Number:ARC50621
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Integrin alpha V (ITGAV/CD51) Rabbit mAb (CAB19071) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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