The KCNJ2 Antibody (CAB12949) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the KCNJ2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for investigations in physiology, neuroscience, and cardiovascular research.The Kir2.1 channel, encoded by the KCNJ2 gene, plays a crucial role in regulating the resting membrane potential and electrical excitability of cells, particularly in the heart and nervous system.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
KCNJ2 Antibody
SKU:
CAB12949
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:
NEIL WGHR YEPV LFEE KHYY KVDY SRFH KTYE VPNT PLCS ARDL AEKK YILS NANS FCYE NEVA LTSK EEDD SENG VPES TSTD TPPD IDLH NQAS VPLE PRPL RRES EI
Tested Applications:
WBIHC-PELISA
Recommended Dilution:
WB
1:500 - 1:2000
IHC-P
1:50 - 1:200
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.
Purification Method
Affinity purification
Gene ID
3759
RRID
AB_2759795
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KCNJ2 Rabbit pAb (CAB12949) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
