The KCNRG Polyclonal Antibody (PACO39418) offered by AssayGenie is specifically designed for researchers studying the KCNRG protein, known for its role in potassium channel regulation. This rabbit-derived antibody is highly reactive with human samples and has been validated for Western blot applications.KCNRG, also known as potassium channel regulator, is involved in the regulation of potassium ion channels, which play a crucial role in cell excitability and neurotransmission. Dysregulation of potassium channels has been implicated in various diseases, including epilepsy and cardiac arrhythmias, making KCNRG an important target for research in these areas.
By using the KCNRG Polyclonal Antibody, researchers can detect and analyze the expression of KCNRG in different cell types, allowing for a better understanding of its functions in various physiological and pathological processes. This antibody is a valuable tool for studies in neuroscience, cardiology, and other fields where potassium channel regulation is of interest.
Antibody Name:
KCNRG Antibody (PACO39418)
Antibody SKU:
PACO39418
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Potassium channel regulatory protein (1-229AA)
KCNRG: Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 13q14.2Cellular Component: endoplasmic reticulumMolecular Function: identical protein binding; protein binding
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein which regulates the activity of voltage-gated potassium channels. This gene is on chromosome 13 and overlaps the gene for tripartite motif containing 13 on the same strand. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
