The KLK1B22 Monoclonal Antibody (PACO34314) is a cutting-edge tool for research involving KLK1B22, a member of the kallikrein-related peptidase family implicated in various physiological processes. This antibody, generated using hybridoma technology, exhibits high specificity and sensitivity for detecting KLK1B22 in human samples, making it a valuable asset for studies in molecular biology and biomedicine.KLK1B22, also known as kallikrein-related peptidase 1B22, is involved in proteolytic cascades that regulate important biological functions such as blood coagulation, fibrinolysis, and inflammation. Its role in these processes suggests its potential as a biomarker for cardiovascular diseases, thrombotic disorders, and inflammatory conditions.
By targeting KLK1B22 with this monoclonal antibody, researchers can gain insights into its function and explore its therapeutic potential in various disease contexts.The PACO34314 antibody is optimized for use in techniques like immunohistochemistry and ELISA, allowing for precise and reliable detection of KLK1B22 in tissue samples and biological fluids. Its superior performance and versatility make it an essential tool for investigating the role of KLK1B22 in health and disease, paving the way for innovative diagnostic and therapeutic strategies in the future.
Antibody Name:
Klk1b22 Antibody (PACO34314)
Antibody SKU:
PACO34314
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Mouse
Immunogen:
Recombinant Mouse Kallikrein 1-related peptidase b22 protein (25-259AA)
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Synonyms:
Kallikrein 1-related peptidase b22 (EC 3.4.21.35) (Beta-NGF-endopeptidase) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Glandular kallikrein K22) (mGK-22) (Nerve growth factor β chain endopeptidase) (Tissue kallikrein 22), Klk1b22, Klk-22 Klk22
UniProt Protein Function:
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
NCBI Summary:
This gene encodes the beta subunit of the 7S nerve growth factor (NGF) complex that is essential for the differentiation and survival of distinct populations of neurons in both the central and the peripheral nervous systems. The encoded preproprotein undergoes proteolytic processing to generate a functional, mature peptide. This gene is located in a cluster of several related kallikrein genes on chromosome 7. [provided by RefSeq, Feb 2016]
