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[KO Validated] LTA4H Rabbit Polyclonal Antibody (CAB19939)

SKU:
CAB19939
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Metabolism
€139 - €419
Frequently bought together:

Description

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Product Name:[KO Validated] LTA4H Rabbit Polyclonal Antibody
SKU:CAB19939
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 312-611 of human LTA4H (NP_000886.1).
Sequence:WDHF WLNE GHTV YLER HICG RLFG EKFR HFNA LGGW GELQ NSVK TFGE THPF TKLV VDLT DIDP DVAY SSVP YEKG FALL FYLE QLLG GPEI FLGF LKAY VEKF SYKS ITTD DWKD FLYS YFKD KVDV LNQV DWNA WLYS PGLP PIKP NYDM TLTN ACIA LSQR WITA KEDD LNSF NATD LKDL SSHQ LNEF LAQT LQRA PLPL GHIK RMQE VYNF NAIN NSEI RFRW LRLC IQSK WEDA IPLA LKMA TEQG RMKF TRPL FKDL AAFD KSHD QAVR TYQE HKAS MHPV TAML VGKD LKVD
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:LTA4H; 4H
Positive Sample:293T
Conjugate:Unconjugated
Cellular Localization:Cytoplasm.
Calculated MW:69kDa
Observed MW:70kDa

The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD). Several transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:4048
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and LTA4H knockout (KO) 293T cells, using [KO Validated] LTA4H Rabbit pAb (CAB19939) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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