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[KO Validated] Rad23A Rabbit Polyclonal Antibody (CAB19884)

SKU:
CAB19884
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
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Description

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Product Name:[KO Validated] Rad23A Rabbit Polyclonal Antibody
SKU:CAB19884
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-363 of human Rad23A (NP_005044.1).
Sequence:MAVT ITLK TLQQ QTFK IRME PDET VKVL KEKI EAEK GRDA FPVA GQKL IYAG KILS DDVP IRDY RIDE KNFV VVMV TKTK AGQG TSAP PEAS PTAA PESS TSFP PAPT SGMS HPPP AARE DKSP SEES APTT SPES VSGS VPSS GSSG REED AAST LVTG SEYE TMLT EIMS MGYE RERV VAAL RASY NNPH RAVE YLLT GIPG SPEP EHGS VQES QVSE QPAT EAAG ENPL EFLR DQPQ FQNM RQVI QQNP ALLP ALLQ QLGQ ENPQ LLQQ ISRH QEQF IQML NEPP GELA DISD VEGE VGAI GEEA PQMN YIQV TPQE KEAI ERLK ALGF PESL VIQA YFAC EKNE NLAA NFLL SQNF DDE
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:HR23A; HHR23A; 3A
Positive Sample:293T
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:40kDa
Observed MW:49kDa

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair. Proteins in this family have a modular domain structure consisting of an ubiquitin-like domain (UbL), ubiquitin-associated domain 1 (UbA1), XPC-binding domain and UbA2. The protein encoded by this gene plays an important role in nucleotide excision repair and also in delivery of polyubiquitinated proteins to the proteasome. Alternative splicing results in multiple transcript variants encoding multiple isoforms.

Purification Method:Affinity purification
Gene ID:5886
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and Rad23A knockout (KO) 293T cells, using [KO Validated] Rad23A Rabbit pAb (CAB19884) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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