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[KO Validated] MST1/STK4 Rabbit Polyclonal Antibody (CAB18100)

SKU:
CAB18100
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] MST1/STK4 Rabbit Polyclonal Antibody
SKU:CAB18100
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 303-487 of human MST1/STK4 (NP_006273.1).
Sequence:KRQE SQQR EVDQ DDEE NSEE DEMD SGTM VRAV GDEM GTVR VAST MTDG ANTM IEHD DTLP SQLG TMVI NAED EEEE GTMK RRDE TMQP AKPS FLEY FEQK EKEN QINS FGKS VPGP LKNS SDWK IPQD GDYE FLKS WTVE DLQK RLLA LDPM MEQE IEEI RQKY QSKR QPIL DAIE AKKR RQQN F
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:KRS2; MST1; YSK3; K4
Positive Sample:HeLa
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:56kDa
Observed MW:60kDa

The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

Purification Method:Affinity purification
Gene ID:6789
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and MST1/STK4 knockout (KO) HeLa cells, using [KO Validated] MST1/STK4 Rabbit pAb (CAB18100) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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